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The tyrosine kinase v‐Src modifies cytotoxicities of anticancer drugs targeting cell division

v‐Src oncogene causes cell transformation through its strong tyrosine kinase activity. We have revealed that v‐Src‐mediated cell transformation occurs at a low frequency and it is attributed to mitotic abnormalities‐mediated chromosome instability. v‐Src directly phosphorylates Tyr‐15 of cyclin‐depe...

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書目詳細資料
發表在:J Cell Mol Med
Main Authors: Yuki, Ryuzaburo, Hagino, Mari, Ueno, Sachi, Kuga, Takahisa, Saito, Youhei, Fukumoto, Yasunori, Yamaguchi, Noritaka, Yamaguchi, Naoto, Nakayama, Yuji
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2021
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7875926/
https://ncbi.nlm.nih.gov/pubmed/33465289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.16270
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