Src Acts as an Effector for Ku70-dependent Suppression of Apoptosis through Phosphorylation of Ku70 at Tyr-530

Src-family tyrosine kinases are widely expressed in many cell types and participate in a variety of signal transduction pathways. Despite the significance of Src in suppression of apoptosis, its mechanism remains poorly understood. Here we show that Src acts as an effector for Ku70-dependent suppres...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Morii, Mariko, Kubota, Sho, Honda, Takuya, Yuki, Ryuzaburo, Morinaga, Takao, Kuga, Takahisa, Tomonaga, Takeshi, Yamaguchi, Noritaka, Yamaguchi, Naoto
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5290942/
https://ncbi.nlm.nih.gov/pubmed/27998981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.753202
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