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v-Src-driven transformation is due to chromosome abnormalities but not Src-mediated growth signaling

v-Src is the first identified oncogene product and has a strong tyrosine kinase activity. Much of the literature indicates that v-Src expression induces anchorage-independent and infinite cell proliferation through continuous stimulation of growth signaling by v-Src activity. Although all of v-Src-e...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Honda, Takuya, Morii, Mariko, Nakayama, Yuji, Suzuki, Ko, Yamaguchi, Noritaka, Yamaguchi, Naoto
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5773541/
https://ncbi.nlm.nih.gov/pubmed/29348492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-19599-1
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