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The tyrosine kinase v‐Src modifies cytotoxicities of anticancer drugs targeting cell division
v‐Src oncogene causes cell transformation through its strong tyrosine kinase activity. We have revealed that v‐Src‐mediated cell transformation occurs at a low frequency and it is attributed to mitotic abnormalities‐mediated chromosome instability. v‐Src directly phosphorylates Tyr‐15 of cyclin‐depe...
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| Udgivet i: | J Cell Mol Med |
|---|---|
| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
John Wiley and Sons Inc.
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7875926/ https://ncbi.nlm.nih.gov/pubmed/33465289 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.16270 |
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