The tyrosine kinase v‐Src modifies cytotoxicities of anticancer drugs targeting cell division

v‐Src oncogene causes cell transformation through its strong tyrosine kinase activity. We have revealed that v‐Src‐mediated cell transformation occurs at a low frequency and it is attributed to mitotic abnormalities‐mediated chromosome instability. v‐Src directly phosphorylates Tyr‐15 of cyclin‐depe...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Yuki, Ryuzaburo, Hagino, Mari, Ueno, Sachi, Kuga, Takahisa, Saito, Youhei, Fukumoto, Yasunori, Yamaguchi, Noritaka, Yamaguchi, Naoto, Nakayama, Yuji
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7875926/
https://ncbi.nlm.nih.gov/pubmed/33465289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.16270
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