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Unraveling the Contribution of Fluid Therapy to the Development of Augmented Renal Clearance in a Piglet Model

Augmented renal clearance (ARC) observed in the critically ill pediatric population has received an increased attention over the last years due to its major impact on the disposition and pharmacokinetics of mainly renally excreted drugs. Apart from an important inflammatory trigger, fluid administra...

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Bibliographic Details
Published in:Front Pharmacol
Main Authors: Dhondt, Laura, Croubels, Siska, De Paepe, Peter, Goethals, Klara, De Cock, Pieter, Devreese, Mathias
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7870502/
https://ncbi.nlm.nih.gov/pubmed/33574754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.607101
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