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Unraveling the Contribution of Fluid Therapy to the Development of Augmented Renal Clearance in a Piglet Model

Augmented renal clearance (ARC) observed in the critically ill pediatric population has received an increased attention over the last years due to its major impact on the disposition and pharmacokinetics of mainly renally excreted drugs. Apart from an important inflammatory trigger, fluid administra...

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Dettagli Bibliografici
Pubblicato in:Front Pharmacol
Autori principali: Dhondt, Laura, Croubels, Siska, De Paepe, Peter, Goethals, Klara, De Cock, Pieter, Devreese, Mathias
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7870502/
https://ncbi.nlm.nih.gov/pubmed/33574754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.607101
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