Augmented Renal Clearance Implies a Need for Increased Amoxicillin-Clavulanic Acid Dosing in Critically Ill Children

There is little data available to guide amoxicillin-clavulanic acid dosing in critically ill children. The primary objective of this study was to investigate the pharmacokinetics of both compounds in this pediatric subpopulation. Patients admitted to the pediatric intensive care unit (ICU) in whom i...

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Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: De Cock, Pieter A. J. G., Standing, Joseph F., Barker, Charlotte I. S., de Jaeger, Annick, Dhont, Evelyn, Carlier, Mieke, Verstraete, Alain G., Delanghe, Joris R., Robays, Hugo, De Paepe, Peter
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2015
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4604416/
https://ncbi.nlm.nih.gov/pubmed/26349821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01368-15
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