Augmented Renal Clearance Implies a Need for Increased Amoxicillin-Clavulanic Acid Dosing in Critically Ill Children

There is little data available to guide amoxicillin-clavulanic acid dosing in critically ill children. The primary objective of this study was to investigate the pharmacokinetics of both compounds in this pediatric subpopulation. Patients admitted to the pediatric intensive care unit (ICU) in whom i...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Main Authors: De Cock, Pieter A. J. G., Standing, Joseph F., Barker, Charlotte I. S., de Jaeger, Annick, Dhont, Evelyn, Carlier, Mieke, Verstraete, Alain G., Delanghe, Joris R., Robays, Hugo, De Paepe, Peter
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2015
Fag:
Pharmacology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4604416/
https://ncbi.nlm.nih.gov/pubmed/26349821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01368-15
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