The Development of a Juvenile Porcine Augmented Renal Clearance Model Through Continuous Infusion of Lipopolysaccharides: An Exploratory Study

Augmented renal clearance (ARC) as observed in the critically ill (pediatric) population can have a major impact on the pharmacokinetics and posology of renally excreted drugs. Although sepsis has been described as a major trigger in the development of ARC in human critically ill patients, mechanist...

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Detalhes bibliográficos
Publicado no:Front Vet Sci
Main Authors: Dhondt, Laura, Croubels, Siska, Temmerman, Robin, De Cock, Pieter, Meyer, Evelyne, Van Den Broeck, Wim, De Paepe, Peter, Devreese, Mathias
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Veterinary Science
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8116505/
https://ncbi.nlm.nih.gov/pubmed/33996970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fvets.2021.639771
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