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Early life imprints the hierarchy of T cell clone sizes

The adaptive immune system responds to pathogens by selecting clones of cells with specific receptors. While clonal selection in response to particular antigens has been studied in detail, it is unknown how a lifetime of exposures to many antigens collectively shape the immune repertoire. Here, usin...

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Detalles Bibliográficos
Publicado en:eLife
Main Authors: Gaimann, Mario U, Nguyen, Maximilian, Desponds, Jonathan, Mayer, Andreas
Formato: Artigo
Idioma:Inglês
Publicado: eLife Sciences Publications, Ltd 2020
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7870140/
https://ncbi.nlm.nih.gov/pubmed/33345776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.61639
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