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Fluctuating fitness shapes the clone-size distribution of immune repertoires

The adaptive immune system relies on the diversity of receptors expressed on the surface of B- and T cells to protect the organism from a vast amount of pathogenic threats. The proliferation and degradation dynamics of different cell types (B cells, T cells, naive, memory) is governed by a variety o...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Desponds, Jonathan, Mora, Thierry, Walczak, Aleksandra M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4720353/
https://ncbi.nlm.nih.gov/pubmed/26711994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1512977112
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