Quantifying selection in immune receptor repertoires

The efficient recognition of pathogens by the adaptive immune system relies on the diversity of receptors displayed at the surface of immune cells. T-cell receptor diversity results from an initial random DNA editing process, called VDJ recombination, followed by functional selection of cells accord...

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Main Authors: Elhanati, Yuval, Murugan, Anand, Callan, Curtis G., Mora, Thierry, Walczak, Aleksandra M.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2014
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4103359/
https://ncbi.nlm.nih.gov/pubmed/24941953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1409572111
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