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Statistical inference of the generation probability of T-cell receptors from sequence repertoires
Stochastic rearrangement of germline V-, D-, and J-genes to create variable coding sequence for certain cell surface receptors is at the origin of immune system diversity. This process, known as “VDJ recombination”, is implemented via a series of stochastic molecular events involving gene choices an...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3479580/ https://ncbi.nlm.nih.gov/pubmed/22988065 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1212755109 |
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