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Evidence for Shaping of Light Chain Repertoire by Structural Selection
The naïve immunoglobulin (IG) repertoire in the blood differs from the direct output of the rearrangement process. These differences stem from selection that affects the germline gene usage and the junctional nucleotides. A major complication obscuring the details of the selection mechanism in the h...
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| Pubblicato in: | Front Immunol |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Frontiers Media S.A.
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6023962/ https://ncbi.nlm.nih.gov/pubmed/29988361 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01307 |
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