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Dental pulp stem cells model early life and imprinted DNA methylation patterns

Early embryonic stages of pluripotency are modeled for epigenomic studies primarily with human embryonic stem cells (ESC) or induced pluripotent stem cells (iPSCs). For analysis of DNA methylation, however, ESCs and iPSCs do not accurately reflect the DNA methylation levels found in preimplantation...

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Detalhes bibliográficos
Publicado no:Stem Cells
Main Authors: Dunaway, Keith, Goorha, Sarita, Matelski, Lauren, Urraca, Nora, Lein, Pamela J., Korf, Ian, Reiter, Lawrence T., LaSalle, Janine M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5367950/
https://ncbi.nlm.nih.gov/pubmed/28032673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.2563
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