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Early life imprints the hierarchy of T cell clone sizes

The adaptive immune system responds to pathogens by selecting clones of cells with specific receptors. While clonal selection in response to particular antigens has been studied in detail, it is unknown how a lifetime of exposures to many antigens collectively shape the immune repertoire. Here, usin...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Gaimann, Mario U, Nguyen, Maximilian, Desponds, Jonathan, Mayer, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7870140/
https://ncbi.nlm.nih.gov/pubmed/33345776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.61639
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