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Activation of ATM kinase by ROS generated during ionophore-induced mitophagy in human T and B cell malignancies
Ataxia telangiectasia mutated (ATM), a critical DNA damage sensor, also possesses non-nuclear functions owing to its presence in extra-nuclear compartments, including peroxisomes, lysosomes, and mitochondria. ATM is frequently altered in several human cancers. Recently, we and others have shown that...
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| Udgivet i: | Mol Cell Biochem |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7867566/ https://ncbi.nlm.nih.gov/pubmed/32996079 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11010-020-03917-1 |
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