ATM Functions at the Peroxisome to Induce Pexophagy in Response to ROS

Peroxisomes are highly metabolic, autonomously replicating organelles that generate ROS as a by product of fatty acid β-oxidation. Consequently, cells must maintain peroxisome homeostasis, or risk pathologies associated with too few peroxisomes, such as peroxisome biogenesis disorders, or too many p...

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Publicat a:Nat Cell Biol
Autors principals: Zhang, Jiangwei, Tripathi, Durga Nand, Jing, Ji, Alexander, Angela, Kim, Jinhee, Powell, Reid T., Dere, Ruhee, Tait-Mulder, Jacqueline, Lee, Ji-Hoon, Paull, Tanya T., Pandita, Raj K., Charaka, Vijaya K., Pandita, Tej K., Kastan, Michael B., Walker, Cheryl Lyn
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4589490/
https://ncbi.nlm.nih.gov/pubmed/26344566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3230
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