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Pitavastatin attenuates AGEs-induced mitophagy via inhibition of ROS generation in the mitochondria of cardiomyocytes

This study aimed to investigate whether pitavastatin protected against injury induced by advanced glycation end products products (AGEs) in neonatal rat cardiomyocytes, and to examine the underlying mechanisms. Cardiomyocytes of neonatal rats were incubated for 48 hours with AGEs (100μg/mL), recepto...

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Detalhes bibliográficos
Publicado no:J Biomed Res
Main Authors: Zha, Zhimin, Wang, Junhong, Li, Shiling, Guo, Yan
Formato: Artigo
Idioma:Inglês
Publicado em: Editorial Department of Journal of Biomedical Research 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6117602/
https://ncbi.nlm.nih.gov/pubmed/29089470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7555/JBR.31.20160116
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