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Gossypol Inhibits Electron Transport and Stimulates ROS Generation in Yarrowia lipolytica Mitochondria

This work studied the effect of gossypol on the mitochondrial respiratory chain of Yarrowia lipolytica. The compound was shown to inhibit mitochondrial electron transfer and stimulate generation of reactive oxygen species. The inhibition kinetics in oxidation of various substrates (NADH, succinate,...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Arinbasarova, Anna Yu, Medentsev, Alexander G, Krupyanko, Vladimir I
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Bentham Open 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3315064/
https://ncbi.nlm.nih.gov/pubmed/22481982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1874091X01206010011
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