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ATM mediates spermidine-induced mitophagy via PINK1 and Parkin regulation in human fibroblasts
The ATM (ataxia telangiectasia mutated) protein has recently been proposed to play critical roles in the response to mitochondrial dysfunction by initiating mitophagy. Here, we have used ATM-proficient GM00637 cells and ATM-deficient GM05849 cells to investigate the mitophagic effect of spermidine a...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4835770/ https://ncbi.nlm.nih.gov/pubmed/27089984 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep24700 |
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