NOTCH Activation via gp130/STAT3 Signaling Confers Resistance to Chemoradiotherapy

SIMPLE SUMMARY: Resistance to chemoradiotherapy represents a fundamental problem in modern oncology because it exposes patients to the potential negative side-effects of both radiation and chemotherapy without any clinical benefit. This study uncovers that the inflammatory signaling hub STAT3 conspi...

Full description

Saved in:
Bibliographic Details
Published in:Cancers (Basel)
Main Authors: Koerdel, Kristin, Spitzner, Melanie, Meyer, Thomas, Engels, Niklas, Krause, Florian, Gaedcke, Jochen, Conradi, Lena-Christin, Haubrock, Martin, Beißbarth, Tim, Leha, Andreas, Johnsen, Steven A., Ghadimi, B. Michael, Rose-John, Stefan, Grade, Marian, Wienands, Jürgen
Format: Artigo
Language:Inglês
Published: MDPI 2021
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7865718/
https://ncbi.nlm.nih.gov/pubmed/33530306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13030455
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items