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Allosteric activation of proto-oncogene kinase Src by GPCR–beta-arrestin complexes
G protein–coupled receptors (GPCRs) initiate signaling cascades via G-proteins and beta-arrestins (βarr). βarr-dependent actions begin with recruitment of βarr to the phosphorylated receptor tail and are followed by engagement with the receptor core. βarrs are known to act as adaptor proteins bindin...
Gorde:
| Argitaratua izan da: | J Biol Chem |
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| Egile Nagusiak: | , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
American Society for Biochemistry and Molecular Biology
2021
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7864071/ https://ncbi.nlm.nih.gov/pubmed/32978252 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.015400 |
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