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The glucose-sensing transcription factor ChREBP is targeted by proline hydroxylation

Cellular energy demands are met by uptake and metabolism of nutrients like glucose. The principal transcriptional regulator for adapting glycolytic flux and downstream pathways like de novo lipogenesis to glucose availability in many cell types is carbohydrate response element–binding protein (ChREB...

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Veröffentlicht in:J Biol Chem
Hauptverfasser: Heidenreich, Steffi, Weber, Pamela, Stephanowitz, Heike, Petricek, Konstantin M., Schütte, Till, Oster, Moritz, Salo, Antti M., Knauer, Miriam, Goehring, Isabel, Yang, Na, Witte, Nicole, Schumann, Anne, Sommerfeld, Manuela, Muenzner, Matthias, Myllyharju, Johanna, Krause, Eberhard, Schupp, Michael
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7863887/
https://ncbi.nlm.nih.gov/pubmed/33023907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.014402
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