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The glucose-sensing transcription factor ChREBP is targeted by proline hydroxylation

Cellular energy demands are met by uptake and metabolism of nutrients like glucose. The principal transcriptional regulator for adapting glycolytic flux and downstream pathways like de novo lipogenesis to glucose availability in many cell types is carbohydrate response element–binding protein (ChREB...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Biol Chem
Egile Nagusiak: Heidenreich, Steffi, Weber, Pamela, Stephanowitz, Heike, Petricek, Konstantin M., Schütte, Till, Oster, Moritz, Salo, Antti M., Knauer, Miriam, Goehring, Isabel, Yang, Na, Witte, Nicole, Schumann, Anne, Sommerfeld, Manuela, Muenzner, Matthias, Myllyharju, Johanna, Krause, Eberhard, Schupp, Michael
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7863887/
https://ncbi.nlm.nih.gov/pubmed/33023907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.014402
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