The glucose-sensing transcription factor ChREBP is targeted by proline hydroxylation

Cellular energy demands are met by uptake and metabolism of nutrients like glucose. The principal transcriptional regulator for adapting glycolytic flux and downstream pathways like de novo lipogenesis to glucose availability in many cell types is carbohydrate response element–binding protein (ChREB...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Main Authors: Heidenreich, Steffi, Weber, Pamela, Stephanowitz, Heike, Petricek, Konstantin M., Schütte, Till, Oster, Moritz, Salo, Antti M., Knauer, Miriam, Goehring, Isabel, Yang, Na, Witte, Nicole, Schumann, Anne, Sommerfeld, Manuela, Muenzner, Matthias, Myllyharju, Johanna, Krause, Eberhard, Schupp, Michael
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Gene Regulation
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7863887/
https://ncbi.nlm.nih.gov/pubmed/33023907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.014402
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