The glucose-sensing transcription factor ChREBP is targeted by proline hydroxylation

Cellular energy demands are met by uptake and metabolism of nutrients like glucose. The principal transcriptional regulator for adapting glycolytic flux and downstream pathways like de novo lipogenesis to glucose availability in many cell types is carbohydrate response element–binding protein (ChREB...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Heidenreich, Steffi, Weber, Pamela, Stephanowitz, Heike, Petricek, Konstantin M., Schütte, Till, Oster, Moritz, Salo, Antti M., Knauer, Miriam, Goehring, Isabel, Yang, Na, Witte, Nicole, Schumann, Anne, Sommerfeld, Manuela, Muenzner, Matthias, Myllyharju, Johanna, Krause, Eberhard, Schupp, Michael
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2020
Matèries:
Gene Regulation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7863887/
https://ncbi.nlm.nih.gov/pubmed/33023907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.014402
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