Downregulation of miR‐326 and its host gene β‐arrestin1 induces pro‐survival activity of E2F1 and promotes medulloblastoma growth

Persistent mortality rates of medulloblastoma (MB) and severe side effects of the current therapies require the definition of the molecular mechanisms that contribute to tumor progression. Using cultured MB cancer stem cells and xenograft tumors generated in mice, we show that low expression of miR‐...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Oncol
Prif Awduron: Miele, Evelina, Po, Agnese, Mastronuzzi, Angela, Carai, Andrea, Besharat, Zein Mersini, Pediconi, Natalia, Abballe, Luana, Catanzaro, Giuseppina, Sabato, Claudia, De Smaele, Enrico, Canettieri, Gianluca, Di Marcotullio, Lucia, Vacca, Alessandra, Mai, Antonello, Levrero, Massimo, Pfister, Stefan M., Kool, Marcel, Giangaspero, Felice, Locatelli, Franco, Ferretti, Elisabetta
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2020
Pynciau:
Research Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7858128/
https://ncbi.nlm.nih.gov/pubmed/32920979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12800
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