Downregulation of miR‐326 and its host gene β‐arrestin1 induces pro‐survival activity of E2F1 and promotes medulloblastoma growth

Persistent mortality rates of medulloblastoma (MB) and severe side effects of the current therapies require the definition of the molecular mechanisms that contribute to tumor progression. Using cultured MB cancer stem cells and xenograft tumors generated in mice, we show that low expression of miR‐...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Mol Oncol
Κύριοι συγγραφείς: Miele, Evelina, Po, Agnese, Mastronuzzi, Angela, Carai, Andrea, Besharat, Zein Mersini, Pediconi, Natalia, Abballe, Luana, Catanzaro, Giuseppina, Sabato, Claudia, De Smaele, Enrico, Canettieri, Gianluca, Di Marcotullio, Lucia, Vacca, Alessandra, Mai, Antonello, Levrero, Massimo, Pfister, Stefan M., Kool, Marcel, Giangaspero, Felice, Locatelli, Franco, Ferretti, Elisabetta
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: John Wiley and Sons Inc. 2020
Θέματα:
Research Articles
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7858128/
https://ncbi.nlm.nih.gov/pubmed/32920979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12800
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