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Properdin oligomers adopt rigid extended conformations supporting function
Properdin stabilizes convertases formed upon activation of the complement cascade within the immune system. The biological activity of properdin depends on the oligomerization state, but whether properdin oligomers are rigid and how their structure links to function remains unknown. We show by combi...
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| Foilsithe in: | eLife |
|---|---|
| Main Authors: | , , , , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
eLife Sciences Publications, Ltd
2021
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7857727/ https://ncbi.nlm.nih.gov/pubmed/33480354 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.63356 |
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