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Crystallization and X-ray analysis of monodisperse human properdin

The 54 kDa protein properdin, also known as factor P (FP), plays a major role in the complement system through the stabilization of the alternative pathway convertases. FP circulates in the blood as cyclic dimers, trimers and tetramers, and this heterogeneity challenges detailed structural insight i...

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Detalhes bibliográficos
Publicado no:Acta Crystallogr F Struct Biol Commun
Main Authors: Pedersen, Dennis Vestergaard, Revel, Margot, Gadeberg, Trine Amalie Fogh, Andersen, Gregers Rom
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6360440/
https://ncbi.nlm.nih.gov/pubmed/30713161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X18018150
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