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Crystallization and X-ray analysis of monodisperse human properdin

The 54 kDa protein properdin, also known as factor P (FP), plays a major role in the complement system through the stabilization of the alternative pathway convertases. FP circulates in the blood as cyclic dimers, trimers and tetramers, and this heterogeneity challenges detailed structural insight i...

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Dettagli Bibliografici
Pubblicato in:Acta Crystallogr F Struct Biol Commun
Autori principali: Pedersen, Dennis Vestergaard, Revel, Margot, Gadeberg, Trine Amalie Fogh, Andersen, Gregers Rom
Natura: Artigo
Lingua:Inglês
Pubblicazione: International Union of Crystallography 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6360440/
https://ncbi.nlm.nih.gov/pubmed/30713161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X18018150
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