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Raman spectral imaging of (13)C(2)H(15)N-labeled α-synuclein amyloid fibrils in cells

Parkinson’s disease is characterized by the intracellular accumulation of α-synuclein (α-syn) amyloid fibrils, which are insoluble, β-sheet-rich protein aggregates. Raman spectroscopy is a powerful technique that reports on intrinsic molecular vibrations such as the coupled vibrational modes of the...

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Detalhes bibliográficos
Publicado no:Biophys Chem
Main Authors: Watson, Matthew D., Flynn, Jessica D., Lee, Jennifer C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7856057/
https://ncbi.nlm.nih.gov/pubmed/33418468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpc.2020.106528
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