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Structural features of α-synuclein amyloid fibrils revealed by Raman spectroscopy

Parkinson's disease (PD) is associated with the formation of α-synuclein amyloid fibrils. Elucidating the role of these β-sheet-rich fibrils in disease progression is crucial; however, collecting detailed structural information on amyloids is inherently difficult because of their insoluble, non...

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Vydáno v:J Biol Chem
Hlavní autoři: Flynn, Jessica D., McGlinchey, Ryan P., Walker, Robert L., Lee, Jennifer C.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5777252/
https://ncbi.nlm.nih.gov/pubmed/29191831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.812388
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