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Segmental (13)C-labeling and Raman Microspectroscopy of α-Synuclein Amyloid Formation
Mapping conformational changes of α-synuclein (α-syn) from soluble, unstructured monomers to β-sheet-rich aggregates is crucial towards understanding amyloid formation. Here, we use Raman microspectroscopy to spatially resolve conformational heterogeneity of amyloid aggregates and monitor amyloid fo...
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| Yayımlandı: | Angew Chem Int Ed Engl |
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| Asıl Yazarlar: | , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2018
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6688611/ https://ncbi.nlm.nih.gov/pubmed/30371967 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201809865 |
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