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The hot sites of α-synuclein in amyloid fibril formation
The role of alpha-synuclein (αS) amyloid fibrillation has been recognized in various neurological diseases including Parkinson’s Disease (PD). In early stages, fibrillation occurs by the structural transition from helix to extended states in monomeric αS followed by the formation of beta-sheets. Thi...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7376172/ https://ncbi.nlm.nih.gov/pubmed/32699326 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-68887-2 |
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