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The hot sites of α-synuclein in amyloid fibril formation
The role of alpha-synuclein (αS) amyloid fibrillation has been recognized in various neurological diseases including Parkinson’s Disease (PD). In early stages, fibrillation occurs by the structural transition from helix to extended states in monomeric αS followed by the formation of beta-sheets. Thi...
Guardat en:
| Publicat a: | Sci Rep |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7376172/ https://ncbi.nlm.nih.gov/pubmed/32699326 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-68887-2 |
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