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CTLA4-Ig prolongs graft survival specifically in young but not old mice
Elderly organ transplant recipients have remained underrepresented in clinical trials, despite representing a rapidly growing population. Here, we assessed age-specific effects of CTLA4-Ig, a fusion protein blocking costimulatory signaling between APCs and T cells through CD28. Cardiac allografts in...
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| I publikationen: | Am J Transplant |
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| Huvudupphovsmän: | , , , , , , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2020
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7855762/ https://ncbi.nlm.nih.gov/pubmed/32717114 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.16218 |
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