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Enhanced GABAergic Inhibition of Cholinergic Interneurons in the zQ175(+/−) Mouse Model of Huntington's Disease

Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder that initially manifests itself in the striatum. How intrastriatal circuitry is altered by the disease is poorly understood. To help fill this gap, the circuitry linking spiny projection neurons (SPNs) to cholinergic...

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Bibliografski detalji
Izdano u:Front Syst Neurosci
Glavni autori: Lim, Sean Austin O., Surmeier, D. James
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2021
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7854471/
https://ncbi.nlm.nih.gov/pubmed/33551760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnsys.2020.626412
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