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Enhanced GABAergic Inhibition of Cholinergic Interneurons in the zQ175(+/−) Mouse Model of Huntington's Disease

Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder that initially manifests itself in the striatum. How intrastriatal circuitry is altered by the disease is poorly understood. To help fill this gap, the circuitry linking spiny projection neurons (SPNs) to cholinergic...

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Bibliografische gegevens
Gepubliceerd in:Front Syst Neurosci
Hoofdauteurs: Lim, Sean Austin O., Surmeier, D. James
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2021
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7854471/
https://ncbi.nlm.nih.gov/pubmed/33551760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnsys.2020.626412
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