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Enhanced GABAergic Inhibition of Cholinergic Interneurons in the zQ175(+/−) Mouse Model of Huntington's Disease

Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder that initially manifests itself in the striatum. How intrastriatal circuitry is altered by the disease is poorly understood. To help fill this gap, the circuitry linking spiny projection neurons (SPNs) to cholinergic...

詳細記述

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書誌詳細
出版年:Front Syst Neurosci
主要な著者: Lim, Sean Austin O., Surmeier, D. James
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Media S.A. 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7854471/
https://ncbi.nlm.nih.gov/pubmed/33551760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnsys.2020.626412
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