Cholinergic Interneurons Amplify Corticostriatal Synaptic Responses in the Q175 Model of Huntington’s Disease

Huntington’s disease (HD) is a neurodegenerative disorder characterized by deficits in movement control that are widely viewed as stemming from pathophysiological changes in the striatum. Giant, aspiny cholinergic interneurons (ChIs) are key elements in the striatal circuitry controlling movement, b...

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Detalhes bibliográficos
Publicado no:Front Syst Neurosci
Main Authors: Tanimura, Asami, Lim, Sean Austin O., Aceves Buendia, Jose de Jesus, Goldberg, Joshua A., Surmeier, D. James
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5159611/
https://ncbi.nlm.nih.gov/pubmed/28018188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnsys.2016.00102
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