Cholinergic Interneurons Amplify Corticostriatal Synaptic Responses in the Q175 Model of Huntington’s Disease

Huntington’s disease (HD) is a neurodegenerative disorder characterized by deficits in movement control that are widely viewed as stemming from pathophysiological changes in the striatum. Giant, aspiny cholinergic interneurons (ChIs) are key elements in the striatal circuitry controlling movement, b...

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Bibliografische gegevens
Gepubliceerd in:Front Syst Neurosci
Hoofdauteurs: Tanimura, Asami, Lim, Sean Austin O., Aceves Buendia, Jose de Jesus, Goldberg, Joshua A., Surmeier, D. James
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2016
Onderwerpen:
Neuroscience
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5159611/
https://ncbi.nlm.nih.gov/pubmed/28018188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnsys.2016.00102
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