MCL-1 is essential for survival but dispensable for metabolic fitness of FOXP3(+) regulatory T cells

FOXP3(+) regulatory T (Treg) cells are essential for maintaining immunological tolerance. Given their importance in immune-related diseases, cancer and obesity, there is increasing interest in targeting the Treg cell compartment therapeutically. New pharmacological inhibitors that specifically targe...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Cell Death Differ
Auteurs principaux: Teh, Charis E., Robbins, Alissa K., Henstridge, Darren C., Dewson, Grant, Diepstraten, Sarah T., Kelly, Gemma, Febbraio, Mark A., Gabriel, Sarah S., O’Reilly, Lorraine A., Strasser, Andreas, Gray, Daniel H. D.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2020
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7853142/
https://ncbi.nlm.nih.gov/pubmed/32612106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-020-0585-1
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires