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MCL-1 is essential for survival but dispensable for metabolic fitness of FOXP3(+) regulatory T cells
FOXP3(+) regulatory T (Treg) cells are essential for maintaining immunological tolerance. Given their importance in immune-related diseases, cancer and obesity, there is increasing interest in targeting the Treg cell compartment therapeutically. New pharmacological inhibitors that specifically targe...
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| 出版年: | Cell Death Differ |
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| 主要な著者: | , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7853142/ https://ncbi.nlm.nih.gov/pubmed/32612106 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-020-0585-1 |
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