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MCL-1 is essential for survival but dispensable for metabolic fitness of FOXP3(+) regulatory T cells
FOXP3(+) regulatory T (Treg) cells are essential for maintaining immunological tolerance. Given their importance in immune-related diseases, cancer and obesity, there is increasing interest in targeting the Treg cell compartment therapeutically. New pharmacological inhibitors that specifically targe...
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| Publicado no: | Cell Death Differ |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7853142/ https://ncbi.nlm.nih.gov/pubmed/32612106 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-020-0585-1 |
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