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MCL-1 is essential for survival but dispensable for metabolic fitness of FOXP3(+) regulatory T cells

FOXP3(+) regulatory T (Treg) cells are essential for maintaining immunological tolerance. Given their importance in immune-related diseases, cancer and obesity, there is increasing interest in targeting the Treg cell compartment therapeutically. New pharmacological inhibitors that specifically targe...

詳細記述

保存先:
書誌詳細
出版年:Cell Death Differ
主要な著者: Teh, Charis E., Robbins, Alissa K., Henstridge, Darren C., Dewson, Grant, Diepstraten, Sarah T., Kelly, Gemma, Febbraio, Mark A., Gabriel, Sarah S., O’Reilly, Lorraine A., Strasser, Andreas, Gray, Daniel H. D.
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7853142/
https://ncbi.nlm.nih.gov/pubmed/32612106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-020-0585-1
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