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Defects in the ‘Bcl-2-regulated’ apoptotic pathway leads to preferential increase of CD25(low)FoxP3(+) anergic CD4(+) T cells
Defects in the 'Bcl-2-regulated' apoptotic pathway inhibit the deletion of self-reactive T cells. What is unresolved, however, is the nature and fate of such self-reactive T cells escaping deletion. Here, we report that mice with such defects contained increased numbers of CD25(low)FoxP3(+...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3150360/ https://ncbi.nlm.nih.gov/pubmed/21742968 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1100027 |
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