The anti-apoptotic activities of Rel and RelA required during B-cell maturation involve the regulation of Bcl-2 expression

Rel and RelA, individually dispensable for lymphopoiesis, serve unique functions in activated B and T cells. Here their combined roles in lymphocyte development were examined in chimeric mice repopulated with c-rel(–/–) rela(–/–) fetal liver hemopoietic stem cells. Mice engrafted with double-mutant...

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Pubblicato in:	EMBO J
Autori principali:	Grossmann, Mathis, O’Reilly, Lorraine A., Gugasyan, Raffi, Strasser, Andreas, Adams, Jerry M., Gerondakis, Steve
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Publishing Group 2000
Soggetti:	Articles
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC305873/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11101508/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.23.6351
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