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The anti-apoptotic activities of Rel and RelA required during B-cell maturation involve the regulation of Bcl-2 expression

Rel and RelA, individually dispensable for lymphopoiesis, serve unique functions in activated B and T cells. Here their combined roles in lymphocyte development were examined in chimeric mice repopulated with c-rel(–/–) rela(–/–) fetal liver hemopoietic stem cells. Mice engrafted with double-mutant...

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Hlavní autoři: Grossmann, Mathis, O’Reilly, Lorraine A., Gugasyan, Raffi, Strasser, Andreas, Adams, Jerry M., Gerondakis, Steve
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2000
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC305873/
https://ncbi.nlm.nih.gov/pubmed/11101508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.23.6351
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