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The anti-apoptotic activities of Rel and RelA required during B-cell maturation involve the regulation of Bcl-2 expression
Rel and RelA, individually dispensable for lymphopoiesis, serve unique functions in activated B and T cells. Here their combined roles in lymphocyte development were examined in chimeric mice repopulated with c-rel(–/–) rela(–/–) fetal liver hemopoietic stem cells. Mice engrafted with double-mutant...
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| 發表在: | EMBO J |
|---|---|
| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group
2000
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC305873/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11101508/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.23.6351 |
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