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The anti-apoptotic activities of Rel and RelA required during B-cell maturation involve the regulation of Bcl-2 expression
Rel and RelA, individually dispensable for lymphopoiesis, serve unique functions in activated B and T cells. Here their combined roles in lymphocyte development were examined in chimeric mice repopulated with c-rel(–/–) rela(–/–) fetal liver hemopoietic stem cells. Mice engrafted with double-mutant...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2000
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC305873/ https://ncbi.nlm.nih.gov/pubmed/11101508 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.23.6351 |
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