Pervasive Genomic Damage in Experimental Intracerebral Hemorrhage: Therapeutic Potential of a Mechanistic-Based Carbon Nanoparticle

Therapy for intracerebral hemorrhage (ICH) remains elusive, in part dependent on the severity of the hemorrhage itself as well as multiple deleterious effects of blood and its breakdown products such as hemin and free iron. While oxidative injury and genomic damage have been seen following ICH, the...

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Pubblicato in:ACS Nano
Autori principali: Dharmalingam, Prakash, Talakatta, Girish, Mitra, Joy, Wang, Haibo, Derry, Paul J., Nilewski, Lizanne Greer, McHugh, Emily A., Fabian, Roderic H., Mendoza, Kimberly, Vasquez, Velmarini, Hegde, Pavana M., Kakadiaris, Eugenia, Roy, Trenton, Boldogh, Istvan, Hegde, Venkatesh L., Mitra, Sankar, Tour, James M., Kent, Thomas A., Hegde, Muralidhar L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7850811/
https://ncbi.nlm.nih.gov/pubmed/32049495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsnano.9b05821
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