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A multi-faceted genotoxic network of alpha-synuclein in the nucleus and mitochondria of dopaminergic neurons in Parkinson’s disease: Emerging concepts and challenges

α-Synuclein is a hallmark amyloidogenic protein component of the Lewy bodies (LBs) that are found in dopaminergic neurons affected by Parkinson’s disease (PD). Despite an enormous increase in emerging knowledge, the mechanism(s) of α-synuclein neurobiology and crosstalk among pathological events tha...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Prog Neurobiol
Päätekijät: Vasquez, Velmarini, Mitra, Joy, Wang, Haibo, Hegde, Pavana M., Rao, K.S., Hegde, Muralidhar L.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7098698/
https://ncbi.nlm.nih.gov/pubmed/31863801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pneurobio.2019.101729
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