Targeting of plasminogen activator inhibitor-1 activity promotes elimination of chronic myeloid leukemia stem cells

Therapeutic strategies that target leukemic stem cells (LSC) provide potential advantages in the treatment of chronic myeloid leukemia (CML). Here we showed that selective blockade of plasminogen activator inhibitor-1 (PAI-1) enhances the susceptibility of CML-LSC to tyrosine kinase inhibitor (TKI),...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Haematologica
Main Authors: Yahata, Takashi, Ibrahim, Abd Aziz, Hirano, Ken-ichi, Muguruma, Yukari, Naka, Kazuhito, Hozumi, Katsuto, Vaughan, Douglas E., Miyata, Toshio, Ando, Kiyoshi
Format: Artigo
Sprog:Inglês
Udgivet: Fondazione Ferrata Storti 2020
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7849585/
https://ncbi.nlm.nih.gov/pubmed/32001531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2019.230227
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker