Inhibition of plasminogen activator inhibitor-1 attenuates against intestinal fibrosis in mice

BACKGROUND/AIMS: Intestinal fibrosis is a major complication of Crohn’s disease (CD). The profibrotic protein transforming growth factor-β (TGF-β) has been considered to be critical for the induction of the fibrotic program. TGF-β has the ability to induce not only the expression of extracellular ma...

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Publicat a:Intest Res
Autors principals: Imai, Jin, Yahata, Takashi, Ichikawa, Hitoshi, Ibrahim, Abd Aziz, Yazawa, Masaki, Sumiyoshi, Hideaki, Inagaki, Yutaka, Matsushima, Masashi, Suzuki, Takayoshi, Mine, Tetsuya, Ando, Kiyoshi, Miyata, Toshio, Hozumi, Katsuto
Format: Artigo
Idioma:Inglês
Publicat: Korean Association for the Study of Intestinal Diseases 2020
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7206341/
https://ncbi.nlm.nih.gov/pubmed/32050315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5217/ir.2019.00037
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