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Prostaglandin E(2) stimulates cAMP signaling and resensitizes human leukemia cells to glucocorticoid-induced cell death
Glucocorticoid (GC) resistance remains a clinical challenge in pediatric acute lymphoblastic leukemia where response to GC is a reliable prognostic indicator. To identify GC resistance pathways, we conducted a genome-wide, survival-based, short hairpin RNA screen in murine T-cell acute lymphoblastic...
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| Udgivet i: | Blood |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society of Hematology
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7845005/ https://ncbi.nlm.nih.gov/pubmed/33507291 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2020005712 |
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