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γ-Glutamyl carboxylase mutations differentially affect the biological function of vitamin K–dependent proteins
γ-Glutamyl carboxylase (GGCX) is an integral membrane protein that catalyzes posttranslational carboxylation of a number of vitamin K–dependent (VKD) proteins involved in a wide variety of physiologic processes, including blood coagulation, vascular calcification, and bone metabolism. Naturally occu...
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| Publicado no: | Blood |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7845004/ https://ncbi.nlm.nih.gov/pubmed/33507293 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2020006329 |
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