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Evaluation of oral anticoagulants with vitamin K epoxide reductase in its native milieu

Warfarin, acenocoumarol, phenprocoumon, and fluindione are commonly prescribed oral anticoagulants for the prevention and treatment of thromboembolic disorders. These anticoagulants function by impairing the biosynthesis of active vitamin K–dependent coagulation factors through the inhibition of vit...

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Pubblicato in:Blood
Autori principali: Chen, Xuejie, Jin, Da-Yun, Stafford, Darrel W., Tie, Jian-Ke
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6213321/
https://ncbi.nlm.nih.gov/pubmed/30089628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2018-05-846592
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