A novel vitamin K derived anticoagulant tolerant to genetic variations of vitamin K epoxide reductase

BACKGROUND: Vitamin K antagonists (VKAs), such as warfarin, have remained the cornerstone of oral anticoagulation therapy in the prevention and treatment of thromboembolism for over half a century. They function by impairing the biosynthesis of vitamin K-dependent (VKD) clotting factors through the...

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發表在:J Thromb Haemost
Main Authors: Chen, Xuejie, Liu, Yizhou, Furukawa, Natsuko, Jin, Da-Yun, Savage, G. Paul, Stafford, Darrel W., Suhara, Yoshitomo, Williams, Craig M., Tie, Jian-Ke
格式: Artigo
語言:Inglês
出版: 2021
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7925372/
https://ncbi.nlm.nih.gov/pubmed/33314621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.15209
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