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Engineer P. multocida Heparosan Synthase 2 (PmHS2) for Size-Controlled Synthesis of Longer Heparosan Oligosaccharides
Pasteurella multocida heparosan synthase 2 (PmHS2) is a dual-function polysaccharide synthase having both α1–4-N-acetylglucosaminyltransferase (α1–4-GlcNAcT) and β1–4-glucuronyltransferase (β1–4-GlcAT) activities located in two separate catalytic domains. We found that removing PmHS2 N-terminal 80-a...
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| Veröffentlicht in: | ACS Catal |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7842274/ https://ncbi.nlm.nih.gov/pubmed/33520345 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscatal.0c01231 |
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